Microbioreactors

Our award-winning microbioreactor systems are equipped with innovative technologies and patented components that are able to revolutionize cell culture. It’s intuitive, easy to use and compatibly used with 96-well and 24-well plates. Whether it is cell line development, biologics production, or drug screening, our microbioreactors can help to offer a much healthier culture environment, shorten the process time and eventually, find the best clones faster.

Why Our Microbioreactors?

Productivity

The high-throughput fashion
enhances productivity and
efficiency in workflows

Flexibility

Optimized and up-scalable
systems that offer
personalized experience

Reliability

Precise control system with
optimal conditions for cell growth
and viability

Versatility

Supporting a wide range of
application areas

Intelligence

Controlled by software with
intuitive interface &
intelligent design

Advancing Discovery

Find better clones faster

What
Is It For?

Biopharmaceutical
Industry

Academic
Institutions

Life Sciences
Startups

Government
Research Facilities

CRO/CDMO

Biopharmaceutical
Industry

Life Sciences
Startups

CRO/CDMO

Academic
Institutions

Government
Research Facilities

Featured
Applications

Cell line development

High yield protein production

Virus production

Spheroid, organoid
& 3D culture

Stem cell & Cell therapy

Product Comparison

Compare our products and choose what you need.
Optimized for
Throughput
Mixing capability
Oxygen transfer rate
CO2 control incubation
Temperature control incubation
Improved edge effect
Humidity monitoring
Water reservoir
UV sterilization
DO/pH/OCR/ECAR real-time monitoring
Automation
Target application
Use cases
S.NEST
24/96-well plate mixing, and real-time DO/pH/OCR/ECAR monitoring
24-well plate*4
Strong
High
Single cell expansion
Early-stage clone selection
Medium optimization
Miniaturized model for process development
Analysis of cell metabolism
Therapeutic antibodies
Cell therapies
C.NEST
24/96-well plate mixing
24-well plate*4
96-well plate*4
Strong
High
Single cell expansion
Early-stage clone selection
Medium optimization
Miniaturized model for process development
Therapeutic antibodies
Cell therapies
C.BIRD
24/96-well plate mixing
24-well plate*3
96-well plate*3
Standard
Standard
Single cell expansion
Early-stage clone selection
Therapeutic antibodies
Cell therapies

Frequently Asked Questions (FAQs)

The working volume of microbioreactors ranges from 150 to 1600 microliters enabling small-volume screening of expensive reagents in pharmacodynamic studies and drug discovery and progress to lab-scale productivity.

Microbioreactors can cultivate various cell types, from cell lines commonly used for viral vector and monoclonal antibody production to iPSC, T-Cell, and CAR-T cell expansion for gene & cell therapy development.

Microbioreactors are regulated by various sensors connected to a control unit that automatically adjusts the conditions within the reactor without the need for sampling and saving time finding the optimal temperature, pH, and media composition conditions for success.

Microbioreactors are cheaper than traditional bioreactors. They are also compact in design, requiring less space and resources. Microbioreactors reduce the costs of raw materials and labor by shortening the optimization phase and finding the best culture conditions and clones faster.

Microbioreactors are miniature bioreactors for cell culture, tissue engineering, and drug development. They are used to grow small volumes of cells and are a cost-effective alternative to traditional bioreactors. Microbioreactors provide a controlled environment for cell growth, and their small size makes them easy to use and maintain. They are ideal for high-throughput screening, process optimization, and scale-up studies.

Microbioreactors induce positive and negative air pressure to flow into and out of every well. This allows reciprocal mixing and provides a constant supply of oxygen to the cell culture to maintain a healthy environment.

Different types of microbioreactors are available, each with unique features and benefits. The most commonly used types of microbioreactors are:
  • Microfluidic-based microbioreactors
  • Membrane-based microbioreactors
  • Stirred-tank microbioreactors
Microfluidic systems offer exceptional control over flow, enabling the manipulation of fluids at microscale levels. This microfluidic precision is especially advantageous in applications demanding high-throughput experimentation and the monitoring of delicate cell cultures. In contrast, membrane-based microbioreactors rely on mass transfer through semipermeable membranes, which can limit their applicability. Stirred-tank microbioreactors, while dependable for mixing, often lack the fine-tuned control and scalability provided by microfluidic systems.

Ready to create the
future of health?