C.STATION
Automate cell line development–integrating single-cell isolation, imaging and clone selection into one efficient, compliant workflow.
Dispense the Best, Discard the Rest
Multi-parameter cell selection with visual proof of clonality
Image-based dispensing enables gated cell selection based on cell size, roundness, and fluorescence while providing a first proof of clonality. If no cell is detected in the dispensing area—or if multiple cells are present—the droplet is automatically discarded. Only single cells that meet your sorting criteria are dispensed at speeds of ~40 wells per minute.
Selection of Fluorescent Cells
Sort on fluorescence, size, and shape together
Include or exclude labelled cells by green fluorescence (488 nm laser; 561 nm on request), in addition to cell size and roundness, for more precise sorting decisions. Inquire for alternative fluorescence options.
Day-0 3D Well Imaging
Capture clonality before the first cell division
Perform 3D stack imaging of the well as the dispensed single cell settles toward the well bottom, providing in-line clonality evidence before the cell has any opportunity to divide.
Day-X Well Bottom Imaging
Track clone growth from isolation to expansion
Detect single cells in both 96- and 384-well plates. Combined with dispensing, nozzle imaging, and cell settling, Day-X well-bottom imaging provides multiple layers of monoclonality evidence while enabling long-term tracking of clonal outgrowth, confluency, and viable cell density.
Automation Friendly
Designed to integrate into automated workflows
A programmable lid and accessible plate carrier enable seamless integration into automated workflows with virtually any scheduler. Whether used as a standalone instrument, paired with a robotic arm, or incorporated into a fully automated CLD workcell, such as the C.STATION, the system is designed to scale with your automation needs.
Multi-parameter cell selection with visual proof of clonality
Image-based dispensing enables gated cell selection based on cell size, roundness, and fluorescence while providing a first proof of clonality. If no cell is detected in the dispensing area—or if multiple cells are present—the droplet is automatically discarded. Only single cells that meet your sorting criteria are dispensed at speeds of ~40 wells per minute.
Sort on fluorescence, size, and shape together
Include or exclude labelled cells by green fluorescence (488 nm laser; 561 nm on request), in addition to cell size and roundness, for more precise sorting decisions. Inquire for alternative fluorescence options.
Capture clonality before the first cell division
Perform 3D stack imaging of the well as the dispensed single cell settles toward the well bottom, providing in-line clonality evidence before the cell has any opportunity to divide.
Track clone growth from isolation to expansion
Detect single cells in both 96- and 384-well plates. Combined with dispensing, nozzle imaging, and cell settling, Day-X well-bottom imaging provides multiple layers of monoclonality evidence while enabling long-term tracking of clonal outgrowth, confluency, and viable cell density.
Designed to integrate into automated workflows
A programmable lid and accessible plate carrier enable seamless integration into automated workflows with virtually any scheduler. Whether used as a standalone instrument, paired with a robotic arm, or incorporated into a fully automated CLD workcell, such as the C.STATION, the system is designed to scale with your automation needs.
CELL LINE DEVELOPMENT
Selection and cultivation of stable clonal lines for biomanufacturing.
CELL THERAPY & STEM CELLS
Cellular therapeutics, stem cell biology, and advancements in regenerative medicine.
GENE THERAPY
Viral vector development, delivery system optimization, and advanced genomic medicine.
MONOCLONAL ANTIBODIES
Discovery, identification, and characterization of therapeutic antibody candidates.
