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Single Cell Dispensers

UP.SIGHT™ 2^nd GenNEW
Optimized For Proof Of Monoclonality, Colony Tracking, Confluency, & Titer Measurement

F.SIGHT™ 2.0
Optimized For Rapid Dispensing of Fluorescent Cells

C.SIGHT™ 2.0
Optimized for Powerful Dispensing of Unlabeled Cells

B.SIGHT™
Optimized For Rapid Microbial Single-Cell Isolation and Cultivation

F.SIGHT™ OMICS
Optimized For Single-Cell-Omics

F.SIGHT™
Optimized For Affordability And Flexibility

C.SIGHT™
Optimized for Affordable Cell Line Development

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Automated Cell Line Development

C.STATION™

Microplate Washers And Dispensers

C.WASH™ PLUS NEW

C.WASH™

G.PURE™

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Microbioreactors

C.BIRD™

C.NEST™

S.NEST™

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Reagents And Consumables

DISPENSING CARTRIDGE

F.QUANT - Titer Assay Quantification

SOFTWARE

C.STUDIO NEW

LIVE CELL IMAGING AND ANALYSIS

CELLCYTE X™
APPLICATIONS

CELL LINE DEVELOPMENT

CELL THERAPY & STEM CELLS

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Application notes

Written by scientists for scientists, these papers cover a wide range of applications and highlight novel ways to optimize one’s research with our devices, technologies and consumables.

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Cell Line Development | Monoclonal antibodies | Single-cell omics|S.NEST™ | C.NEST™

S/C.NEST – Investigation of seeding density and mixing speed for optimal CHO cell culture in 24-well scale mixing culture

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Cell-Based Assay|C.NEST™ | Microbioreactors

C.NEST – Microbioreactor offers precisely controlled environments for mixing and static cell culture and significantly minimized evaporation and edge effects in well-plates

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Cell-Based Assay | Drug Screening|S.NEST™

S.NEST – A modern screening platform with real-time dissolved oxygen and pH monitoring as novel cytotoxicity assay for drug screening

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Cell Line Development | Cell therapy & Stem cells|UP.SIGHT™

The UP.SIGHT enables gentle single cell clonal expansion of human iPSCs with high clone recovery

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RNA-sequencing | Single-cell omics|F.SIGHT™ OMICS | I.DOT | G.PURE™

User-friendly automation of full-length single-cell RNA-sequencing with FLASH-seq

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Cell imaging|CELLCYTE X™

Monitoring of multi-spheroid growth and health

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Cell imaging|CELLCYTE X™

High-throughput monitoring of drug effects on single-tumor spheroids

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Cell Line Development|S.NEST™

S.NEST – Mass transfer coefficient KLa of the S.NEST microbioreactor

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Cell Line Development | Monoclonal antibodies | Single-cell omics|C.NEST™ | UP.SIGHT™

C.NEST – A novel microbioreactor shortens the single-cell cloning timeline with the single-cell dispenser UP.SIGHT

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Cell Line Development|S.NEST™

S.NEST – An intelligent tool with real-time dissolved oxygen and pH monitoring on batch cultures

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Cell imaging|CELLCYTE X™

CELLCYTE X – Quantitative live cell imaging assays for immunology

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Cell imaging|CELLCYTE X™

CELLCYTE X – High-throughput Spheroid Formation and Migration with TeloCol-10 for Improved Stability

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Cell Line Development | Reduce liquid lost|EZHold™ | C.NEST™ | S.NEST™

EZHold – A Standardized Machine to Lower Liquid Loss after Culturing in C.BIRD, C.NEST, and S.NEST Microbioreactor Systems

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Cell Line Development | ELISA|C.NEST™

C.NEST – Investigation of a multi-scale microplate-based culture system for static culture

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Cell imaging|CELLCYTE X™ | CASY

CELLCYTE X – Determination of Cell Proliferation Using the CELLCYTE X Live-cell Imaging System

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Genomics | Single-cell omics|C.BIRD™

C.BIRD – Improving the single-cell cloning workflow through increasing cell growth rate by C.BIRD mixing culture

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Genomics | Virus Production|C.BIRD™

C.BIRD – Enhancing the Cell Growth and Protein Productivity of Adherent HEK293 Cell Line in 96- and 24-well plates

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Cell therapy & Stem cells|C.BIRD™

C.BIRD – Augment the Human T Cell Activation in Standard 96-well Plates Using the C.BIRD Microbioreactor

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3D Cell Culture | Cell Line Development|C.BIRD™

C.BIRD – An Innovative 3D Cell Culture System for Tumor Spheroid

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Cancer research | Cell-Based Assay|I.DOT | I.DOT Mini

Tumor Spheroid Formation Using the I.DOT

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Genomics | RNA-sequencing | Single-cell omics|I.DOT | F.SIGHT™

Miniaturization and Automation of a full-length Single-Cell RNA-seq Workflow

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Cell Line Development|C.BIRD™

C.BIRD – Providing Optimal Suspension Culture Conditions in 96-well Plates and Superior Comparability with Large-scale Shaker Flask Culture Environments

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Cell Line Development | Gene Therapy|F.SIGHT™ | F.SIGHT™ 2.0 | F.QUANT

F.SIGHT – Fluorescence intensity-based isolation of single cells with assured clonality for CLD workflows

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Cell Line Development | Cell therapy & Stem cells|UP.SIGHT™ | F.SIGHT™ | F.SIGHT™ 2.0

Streamlined Workflow for the Generation of CRISPR-edited Mesenchymal Stem Cell Clones for Regenerative Medicine Applications

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Cell Line Development | Cell therapy & Stem cells | Cell-Based Assay | Gene Therapy | Monoclonal antibodies|UP.SIGHT™ | C.SIGHT™ | C.LIVE Caspase

Combined Single-cell Dispensing and 3D Full Well Imaging for Cell Lines with >99.99% Probability of Monoclonality

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Cell-Based Assay | ELISA | Liquid Handling|C.WASH™ | C.LIVE™ | Dispensing Cartridge | C.WASH Plus™ |

Highly Efficient Washing of Microwell Plates Using Centrifugal Forces

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COVID research | Genomics | Single-cell omics|G.PURE™

Using the C.WASH to conduct automated, non-contact bead-based DNA purification

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Cell Line Development|C.BIRD™

C.BIRD – Incorporation of Optimized Cell Culture Environment in 24-well Plates for Suspension Cells

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Genomics | Single-cell omics|I.DOT

Fast, Miniaturized and Automated Library Prep for High-quality Single-cell RNA-seq Data

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Gene Therapy | Microbiome Research|C.BIRD™

C.BIRD – High-throughput Screening of Recombinant Clones in Microscale

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Cell Line Development|C.BIRD™

C.BIRD – Improving Oxygen Transfer in Standard 96-well Plates Using the C.BIRD Microbioreactor

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Cell imaging|CELLCYTE X™

CELLCYTE X – Kinetic Assessment of Reporter Gene Expression with Live Cell Imaging

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Cell imaging | Cell-Based Assay|CELLCYTE X™

CELLCYTE X – Optimizing Transfection Efficiency with High-throughput Live Cell Imaging

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Genomics | Single-cell omics|G.PURE™

The C.WASH Enables Automated and Tip-free Bead-based DNA Purification with Uniform Results and No Cross-Contamination

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Cell Line Development | Protein Production|C.BIRD™

C.BIRD – An Innovative Cell Culture Method for Hybridoma in Early Stages

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Cell Line Development | Single-cell omics|UP.SIGHT™ | C.SIGHT 2.0™ | F.SIGHT™ 2.0 | F.SIGHT™ OMICS | C.STATION™ |

Acoustophoresis-based Cell Focusing Enables Enhanced Single-cell Dispensing

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Cell therapy & Stem cells|C.BIRD™

C.BIRD – An Innovative Cell Culture for Human T Cells

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Cell imaging | Cell therapy & Stem cells | Cell-Based Assay|CELLCYTE X™

CELLCYTE X – Real-time Multiparametric Pharmacological Screening with Live Cell Imaging

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ELISA|C.WASH™ | C.WASH Plus™

Improved ELISA workflow efficiency using automated plate washing

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Cell Line Development | Cell-Based Assay | Flow Cytometry|C.WASH™ | C.WASH Plus™

C.WASH – Automated noncontact washing of suspension cells

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Microbiome Research | Single-cell omics|B.SIGHT™ | I.DOT

B.SIGHT – Sequencing Single-cell Genomes of Uncultivated Bacteria in the Human Oral Microbiome

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Microbiome Research|B.SIGHT™

B.SIGHT – High-throughput Cultivation Workflow for Isolation of Anaerobic Gut Bacteria

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Cell Line Development|F.SIGHT™ | F.SIGHT™ 2.0

F.SIGHT – Deconvoluting clonal complexity of barcoded cell populations

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Protein expression in microbial systems | Synthetic Biology|B.SIGHT™ | S.NEST™

B.SIGHT – Accelerating bacteria transformation and cloning workflows using microbial single-cell isolation

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COVID research | Genomics | RNA-sequencing | Single-cell omics|G.PURE™

C.WASH allows fast, tip-free bead-based DNA purification for single cell RNA-sequencing

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CYTENA is a part of BICO. BICO is a lab automation partner and provider of selected workflows to pharma and biotech. Operating through three business areas – Lab Automation, Life Science Solutions, and Bioprinting – BICO strives towards the vision to enable and automate the life science lab of the future.

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