C.STATION™

Optimize and streamline entire cell line development (CLD) workflows with this automated, intuitively designed workstation. From single-cell cloning of transfected cells to selecting high-producing clones to upscaling, the all-new C.STATION fully automates stable CLD for monoclonal antibody production.

C.STATION™

Optimize and streamline entire cell line development (CLD) workflows with this automated, intuitively designed workstation. From single-cell cloning of transfected cells to selecting high-producing clones to upscaling, the all-new C.STATION fully automates stable CLD for monoclonal antibody production.

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Key Features & Benefits

Find out how our product can enrich your research

Preconfigured and validated protocols

Optimized and validated protocols help generate stable cell lines and make laboratory automation best practices more accessible.

Flexibility and upscaling

The C.STATION gives you the flexibility to screen hundreds of clones for high titers. Easily upscale CLD by processing multiple runs at once for in-house or contract development manufacturing (CDM).

Proven technology

The C.STATION automates CLD workflows by integrating our proven technologies in single-cell dispensing, assurance of clonality, plate imaging, colony tracking and titer assessment all in a self-contained workstation.

Sterile workflow

HEPA filters within the C.STATION create a sterile environment throughout the entire workflow.

Shorter timelines and better outcomes

The C.STATION is ready to use straight from the box and full automation saves you time normally spent in the planning phase. Our proven technology within the workstation also reduces the risk of failures in the development process.

Single point of contact

CYTENA is your single point of contact for the entire workstation.

Product Details

Discover what you can do

What is inside?

Single-cell cloning to
meet regulatory requirements

The C.STATION integrates CYTENA’s flagship instrument, the UP.SIGHT™, to enable a probability of clonality >99.99% and fulfill required regulatory expectations. Double assurance of clonality is achieved through nozzle images and 3D Full Well Imaging, a new and innovative method that images the full volume of each well from the point of dispensing using the integrated imager. First, images are taken at the dispensing nozzle to ensure only one cell is placed in each well and nonclonal droplets are discarded. Then, the single cells are confirmed once more with 3D Full Well Imaging.
Tracking colony
growth over time
Confluency, cell count and viability of clonal cells are effortlessly monitored by the UP.SIGHT. The C.STUDIO software lets you track growing colonies over the course of an experiment while the instrument enables you to rewind and replay images, providing a full picture of the CLD workflow. With the confluency tool, determine the right time point to pick clones for a larger volume plate format.
Comprehensive mAb titer monitoring for high-producing clone identification
The C.STATION comes with built-in titer quantification based on a plate-based assay using the F.QUANT. This makes it possible to screen hundreds of clones without user interaction. With the C.STUDIO, clone selection based on relative productivity is straight forward and guarantees data traceability.

Product
Applications

Accelerate your research

Automated cell line development

Monoclonal antibody development

Monoclonal cell culture

Gene therapy

Cell therapy

Featured Workflow

With the C.STATION, you will be able to fully automated entire cell line development workflows
with this our intuitively designed workstation. From single-cell cloning of transfected cells to
selecting high-producing clones to upscaling, the C.STATION enables stable and reliable monoclonal antibody production.

Download Application Notes

For scientists by scientists, these notes highlight novel ways to optimize
your research with our products and solutions

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Product Datasheet

Safety Level 1 Safety Level 2
Plate compatibility ANSI SLAS 1-2004 (R2012) ANSI SLAS 1-2004 (R2012)
Plate capacity Up to 60 microtiter plates (< 6-Well format),
Up to 14 deepwell plates
Up to 120 microtiter plates (< 6-Well format),
Up to 28 deepwell plates
Workflows mAbs,
Viral Vector,
Gene Therapy,
iPSC
mAbs,
Viral Vector,
Gene Therapy,
iPSC
Cell Sorting Cell Morphology and Fluorescence on CYTENA
UP.SIGHT
Cell Morphology and Fluorescence on CYTENA
UP.SIGHT
Liquid Handling Hamilton STARlet M Hamilton STARlet M
Minimum – Maximum aspirate/dispense volume 1-1000 µL, 5% CV 1-1000 µL, 5% CV
Incubation 4-50 °C, 0-20 Vol% CO2 static or shaken culture 4-50 °C, 0-20 Vol% CO2 static or shaken culture
Humidity Range < 80% rH shaken,
< 95% static
< 80% rH shaken,
< 95% static
Plate shaking for assays 200-3000 rpm, constant 2 mm diameter 200-3000 rpm, constant 2 mm diameter
Software Green Button Go (Scheduling),
C.STUDIO (Analysis) on Windows
Green Button Go (Scheduling),
C.STUDIO (Analysis) on Windows
Computation Custom Rack PC Custom Rack PC
Footprint (WxDxH)* 3500 x1200 x 2400 mm 4200 x 1400 x 2640 mm
Weight* 1500 kg 2000 kg
Thank you for your interest in our product. We understand that every business has unique needs, and our pricing plans are tailored to meet those needs. For a customized quote and to learn more about our pricing options, please fill out the quote request form. We would be happy to help you find the best plan for your needs and budget and answer any questions you may have. Thank you!

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