Single-cell omics

Unleashing single-cell proteomics: scPICO revolutionizes absolute quantification with F.SIGHT™ & I.DOT™ technology

Single-cell protein quantification is key for exploring cellular heterogeneity but often lacks sensitivity, throughput, or accuracy. The scPICO assay was developed to enable reference-free absolute quantification of proteins at the single-cell level. It combines the F.SIGHT for precise single-cell dispensing and the I.DOT for ultra-low-volume reagent handling. The resulting workflow delivers highly sensitive, high-throughput single-cell proteoform […]

Unleashing single-cell proteomics: scPICO revolutionizes absolute quantification with F.SIGHT™ & I.DOT™ technology Read More »

User-friendly automation of full-length single-cell RNA-sequencing with FLASH-seq

jesperl

Week-22 human retinal organoids were processed with an automated FLASH-seq workflow. The F.SIGHT™ OMICS enabled precise single-cell isolation, the I.DOT™ ensured miniaturized reagent dispensing, and the C.WASH™ provided tip-free purification. Together, these systems made full-length scRNA-seq more efficient, reducing manual effort while ensuring high-quality data. Learn more about how: F.SIGHT OMICS enabled precise single-cell isolation

User-friendly automation of full-length single-cell RNA-sequencing with FLASH-seq Read More »

Miniaturization and Automation of a full-length Single-Cell RNA-seq Workflow

jesperl

Full-length single-cell RNA-seq is often limited by high reagent use and labor-intensive workflows. In this study, the F.SIGHT™ was used to isolate single HEK293FT cells into 384-well PCR plates, followed by automated miniaturized library preparation with the I.DOT™. Our findings demonstrate that the F.SIGHT and I.DOT provide a scalable and cost-efficient platform for high-quality, full-length scRNA-seq.

Miniaturization and Automation of a full-length Single-Cell RNA-seq Workflow Read More »

Using the C.WASH™ to conduct automated, non-contact bead-based DNA purification

jesperl

Magnetic bead cleanup is a manual bottleneck in scRNA-seq workflows, often increasing time and tip consumption. The C.WASH automates this step: it uses centrifugal force to gently remove liquids while retaining magnetic beads, then dispenses wash reagents non-contact, reducing cross-contamination. In a test with alternating human and mouse cells in 384-well plates, C.WASH showed no cross-species contamination

Using the C.WASH™ to conduct automated, non-contact bead-based DNA purification Read More »

Fast, Miniaturized and Automated Library Prep for High-quality Single-cell RNA-seq Data

jesperl

The F.SIGHT™ was used to isolate single HEK293FT cells into 384-well PCR plates, followed by automated miniaturized library preparation with the I.DOT™. Reaction volumes were reduced to one-tenth of the standard, enabling cost-efficient full-length scRNA-seq. This workflow shows how the F.SIGHT together with the I.DOT enable precise single-cell isolation and high-quality sequencing in a scalable,

Fast, Miniaturized and Automated Library Prep for High-quality Single-cell RNA-seq Data Read More »

The C.WASH™ Enables Automated and Tip-free Bead-based DNA Purification with Uniform Results and No Cross-Contamination

jesperl

Automated, tip-free bead-based DNA purification accelerates NGS library preparation while eliminating cross-contamination risks. In this study, the C.WASH gently removed wash buffers via centrifugal force, maintained magnetic beads during cleaning, and uniformly dispensed reagents – avoiding well-to-well contamination and saving over a thousand pipette tips per run. These results underscore the C.WASH as a highly efficient and

The C.WASH™ Enables Automated and Tip-free Bead-based DNA Purification with Uniform Results and No Cross-Contamination Read More »

Acoustophoresis-based Cell Focusing Enables Enhanced Single-cell Dispensing

cytwordpresshb

Acoustophoresis-based cell focusing improves precision in single-cell applications by aligning cells prior to dispensing. In this study, the UP.SIGHT™ was used to enhance cell isolation efficiency, recovery rate, and dispensing speed at low concentrations while maintaining high cell viability. Our findings support the use of the UP.SIGHT as a reliable platform for accurate, fast, and gentle

Acoustophoresis-based Cell Focusing Enables Enhanced Single-cell Dispensing Read More »

B.SIGHT™ – Sequencing Single-cell Genomes of Uncultivated Bacteria in the Human Oral Microbiome

jesperl

Uncultivated bacteria in the human oral microbiome remain largely unexplored, offering opportunities for new discoveries. In this study, the B.SIGHT enabled label-free single-cell isolation with image-based detection, followed by miniaturized MDA that reduced reaction volumes and costs. Subsequent 16S rRNA sequencing allowed taxonomic classification, and because all steps were performed in standard microwell plates, the

B.SIGHT™ – Sequencing Single-cell Genomes of Uncultivated Bacteria in the Human Oral Microbiome Read More »

C.WASH™ allows fast, tip-free bead-based DNA purification for single cell RNA-sequencing

jesperl

Current scRNA-seq workflows are hindered by manual, tip-consuming bead cleanup steps that introduce variability and inefficiency. The C.WASH non-contact plate washer and liquid dispenser automates bead-based DNA purification using centrifugal removal of liquids and integrated reagent dispensing. In tests using alternating rows of human and mouse single cells in 384-well plates, C.WASH eliminated cross-sample contamination and

C.WASH™ allows fast, tip-free bead-based DNA purification for single cell RNA-sequencing Read More »

Customers

Wall of Love

Wall of Love

Application Notes

Publications

Brochures and One-Pagers

Tools and Calculators

Video Library

Blog

Events

Webinars

Customers

Wall of Love

Wall of Love

Application Notes

Publications

Brochures and One-Pagers

Tools and Calculators

Video Library

Blog

Events

Webinars

Single-cell omics