Gene Therapy

F.SIGHT™ – Fluorescence intensity-based isolation of single cells with assured clonality for CLD workflows

Fluorescence-based workflows enhance single-cell cloning efficiency and clonality assurance. In this study, the F.SIGHT was used to isolate fluorescently stained cells, enabling clear viability assessment and direct correlation of GFP expression with gene-of-interest production. Our findings support the use of the F.SIGHT as a reliable platform for fluorescence intensity–based single-cell isolation in CLD workflows. Learn […]

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Combined Single-cell Dispensing and 3D Full Well Imaging for Cell Lines with >99.99% Probability of Monoclonality

Ensuring monoclonality in cell line development is essential yet challenging. In this study, the UP.SIGHT™ combines double verification of single-cell dispensing, via nozzle imaging and novel 3D full-well imaging, to confirm monoclonality (>99.99%) without centrifugation or fluorescent labeling. Compatible with 96-, 384-, and 1536-well plates, the UP.SIGHT enables high-throughput single-cell cloning and colony tracking, with minimal

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