I.DOT™ Liquid Handler

Fast. Precise. Traceable. Revolutionary non-contact dispensing technology that reduces costs while delivering unmatched accuracy from nanoliters to microliters.

Latest technology in non-contact dispensing for fast and reproducible results every time.

The I.DOT is a liquid handler from DISPENDIX that anyone can use regardless of automation experience. The instrument transfers volumes as low as 8 nL with unrivaled precision and speed while dramatically reducing your laboratory's plastics and reagent consumption. Whether you are dispensing enzymes and beads for NGS or qPCR or adding cells, compounds, and buffers for Assay Development or High-Throughput Screening, the I.DOT offers unrivaled precision and ease of use for efficient and reproducible sample preparation.

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Low-Volume Dispensing for Every Lab

Nanoliters & Microliters

MeOH - 65% Glycerol

Nanoliter Resolution

<1 Microliter Dead Volume

Integrated Volume Verification

Shocking Speed, Precision, & Traceability

96 or 384 Sources to Any-well

Join 1,000+ Biopharmaceutical Companies and Academic Institutions

Key Features & Benefits

Find out how our product can enrich your research

Practice Sustainability

Use a fraction of the pipette tips required by traditional automation, save the planet, and retain your budget.

Generate Trustworthy Results

Dispense 8 nL to 30 μL with 0.1 nL resolution into any SBS format destination labware with a high degree of precision.

Forget About
Training

Software for dispensing a constant volume, dilution, normalization, and pooling should not be complicated.

Conserve
Reagents

Dispense reagents with less than 1 μL dead volume and run more samples for the same reagent cost.

Trust Your
Process

Dispense with insight into the actual volume dispensed every time with integrated volume verification and re-dispense missed droplets.

Deliver Value to Your Lab

Dispense up to 384 source liquids per run at a speed and precision that will continue to surprise you and your colleagues every day.

Product Details

Discover what you can do
Fast. Precise. Traceable.

The I.DOT is an intuitive liquid handling system designed for researchers of all experience levels. This breakthrough technology precisely dispenses volumes as low as 8 nL with unrivaled accuracy and speed, while dramatically reducing your laboratory’s plastic waste and reagent consumption.

From dispensing sensitive enzymes and beads for NGS or qPCR to precisely delivering cells, compounds, and buffers for assay development and high-throughput screening, the I.DOT delivers exceptional precision and remarkable ease of use. The result? More efficient workflows and consistently reproducible sample preparation that transforms your research capabilities.

Enabling Miniaturization is Our Passion

Although reaction miniaturization is ubiquitous in large pharmaceutical environments, it can be challenging to understand the risks and considerations associated with generating high-quality data in the context of miniaturizing assays.

The DISPENDIX team has worked through miniaturization of even the most complex NGS workflows—and can help you to scale volumes as low as 1/10th the manufacturer’s recommended SOP without compromising data quality.

Designed for Automation

The I.DOT Liquid Handler has been designed so that I.DOT Source Plates and destination SBS format labware can be reproducibly loaded into the device for reliable integration into any automated work cell.

With a SiLA2 compliant API and comprehensive integration manual, third party integrators can seamlessly and efficiently incorporate the I.DOT into any automated solution to maximize efficiency, reproducibility, and process safety.

Choose the Best Fit for Your Application

Optimized for Flexibility
Full Viscosity Range from Methanol to 65% Glycerol
Up to 96 Source Wells with 1 μL Dead Volume
80 μL Source Well Capacity

Optimized for Genomics
Viscosity Range from Water to 43% Glycerol
Up to 96 Source Wells with 1 μL Dead Volume
500 μL Source Well Capacity
Optimized for Drug Discovery
Designed to dispense DMSO & Aqueous Solutions
Up to 384 Source Wells with 5 μL Dead Volume
80 μL Source Well Capacity

Choose the Right I.DOT For Your Lab

I.DOT

S Plates, Standard Destination

I.DOT DW

S Plates, DW Destination

I.DOT L

L Plates, DW Destination

Source Options

S.60, S.100, S.200 Well plates
support wide range of liquid classes

S.Wells contain 80 µL source volume

S.60, S.100, S.200 Well plates
support wide range of liquid classes

S.Wells contain 80 µL source volume

NEW L.100 Well plates available

L.Wells contain 500 µL source volume making them more convenient for higher volume multi-well dispensers.

Destination Options

Standard

Supports 96 flat plates, 384 and 1536 well plates and
custom plate formats

DW

Supports skirted 96-well PCR plates, Deep-well plates,
SBS standard plates, and custom plate formats

DW

Supports skirted 96-well PCR plates and
Deep-well plates

Product
Applications

Accelerate your research

High-Throughput Screening

Assay Development

CRISPR Reactions

Synthetic Biology

Genomics and Proteomics

Featured Workflow

I.DOT Combats the COVID-19 Pandemic – Given the challenges of combating the COVID-19 pandemic, scientists in both research and diagnostic environments are looking to optimize their workflows for crucial time and cost savings. An influential example is a study conducted by Dr. Nicola Crosetto’s lab at Karolinska Institutet, in which the I.DOT (Immediate Drop-on-demand Technology) liquid handler was used to automate and streamline a versatile technique (COVseq) for preparing multiplex DNA sequencing libraries from low-input samples with high accuracy, speed and significant reductions in liquid reagent volumes.

The study revealed that the COVseq technique can be easily applied to ongoing pandemic genomic surveillance and adapted to monitor other pathogens such as influenza viruses. In addition, an analysis of costs showed that the technique could be used to sequence thousands of samples per week at less than $10 per sample, including library preparation and sequencing costs.

Download Application Notes

For scientists by scientists, these notes highlight novel ways to optimize
your research with our products and solutions

Product Datasheet

Thank you for your interest in our product. We understand that every business has unique needs, and our pricing plans are tailored to meet those needs. For a customized quote and to learn more about our pricing options, please fill out the quote request form. We would be happy to help you find the best plan for your needs and budget and answer any questions you may have. Thank you!

Ready to create the
future of health?