C.STATION™

Find out how our product can enrich your research

The C.STATION integrates all its components in a compact
workstation in either BSL-1 or BSL-2 configuration.

Industrial CLD workflows require consistent results and timelines, which can be hard to achieve with manual workflows. The C.STATION enables the automation of even the most advanced cell culture operations required in CLD, such as harvesting, splitting, and maintenance of suspension and adherent cells over many weeks.

The C.STATION features CYTENA’s proven single-cell dispensing technology, trusted by hundreds of organizations in biologics development. It rapidly dispenses single cells into 96- and 384-well plate formats, delivering best-in-class single-cell cloning efficiency. Designed with gentle technology, it ensures compatibility with even the most delicate cell types, such as HEK cells and iPSCs. Combined with CYTENA’s proprietary z-stack imaging or bottom-well imaging, the C.STATION provides gold-standard, image-based documentation of clonality, fully compliant with IND/BLA submission requirements.

The integration of advanced imaging technology enables day 0 bottom-well imaging, confluency tracking, cell counting, and viability measurements, ensuring fast and accurate clone screening. This seamless integration allows you to select the optimal time point for automated hit picking and plate transfer, based on confluency, cell count, productivity, or other clone screening assay results.

The C.STATION is available in BSL-1 and BSL-2 configurations to match the requirements of diverse laboratories and ensure all the steps of your CLD workflow are performed safely in a controlled and sterile environment.

C.STUDIO software’s clone-centricity makes it simple to keep track of all data collected for each individual clone from the single-cell stage to larger well plate formats or suspension culture in deep well plates. The software supports the identification of the best-performing clones at each step and gives you complete freedom to select the optimal time for clone validation or scaling.

The C.STATION seamlessly integrates technologies for precise measurement of mAb titers, enabling researchers to identify and select high-performing mAb-producing clones. Flexible plate formats and robust data export/import capabilities simplify integration with application-specific analytics, including ddPCR, NGS, and ELISA, for advanced clone characterization and selection.

The C.STUDIO software compiles your clones’ picture during single-cell dispensing, z-stack, and bottom-well imaging in a regulator-ready clonality report to support robust proof of monoclonality. The C.STUDIO is compatible with 21 CFR Part-11, ensuring your data integrity, from collection to reporting.

The Campaign Initializer simplifies the setup and management of CLD campaigns, making complex lab automation accessible to scientists focused on achieving timely and successful outcomes. With its intuitive interface, users can leverage a pre-configured library of methods to seamlessly replicate workflows on the C.STATION. For advanced users, the platform offers powerful customization through Green Button Go scheduling software, delivering unmatched flexibility. Complementing this C.STUDIO and C.SERVICES provide a complete solution for clone-centric data visualization and management, rounding out the suite to streamline every step of CLD workflows.

The C.STATION includes protocols optimized for essential cell lines commonly used in modern therapeutic production, such as CHO, HEK293, Sf9, and iPSCs.