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Linkedin Facebook X-twitter Instagram Mammalian Cell Line Development: Applications and Common Challenges Mammalian cell lines are the cornerstone of translational and basic biomedical research. They provide a relatively cheap and manageable model for countless disease types and are invaluable for the production of many established and cutting-edge therapies1. With the advent of gene editing techniques, […]

Linkedin Facebook X-twitter Instagram Innovations and Applications of Single-Cell Seeding Advanced single-cell seeding processes continue to revolutionize biomedical research and therapeutic production by ensuring precision and purity. Single-cell seeding minimizes variability and ensures clonality, allowing it to support critical therapeutic areas such as regenerative medicine and oncology. Single-cell seeding accelerates advanced therapy development and high-throughput

Linkedin Facebook X-twitter Instagram Single-Cell Seeding: From Basics to Advanced Methods The single-cell seeding process differs across laboratories and institutions, and there are many ways to perform single-cell seeding depending on the resources and equipment available1. While these methods can produce clonally distinct populations growing in a single well, they come with varying degrees of

Linkedin Facebook X-twitter Instagram Applications of Single-Cell Seeding in Biomedical Research Single-cell seeding is revolutionizing biomedical research, offering unprecedented disease insights and treatment options in various fields. Its applications span a range of disease states and drug development phases. Regenerative medicine using induced pluripotent stem cells (iPSCs) benefits immensely, as single genetically modified stem cells

Linkedin Facebook X-twitter Instagram Precision in Single-Cell Seeding: Key Strategies for Success In cell line development (CLD), generating high-quality, monoclonal cell populations is essential for therapeutic and research applications1. Precision single-cell seeding plays a vital role in this process, enhancing cell line purity, scalability, the isolation of rare cells, and aiding regulatory compliance. Robust quality

Linkedin Facebook X-twitter Instagram The Ultimate Guide to Laboratory Automation and Related Instruments Automation has revolutionized numerous industries, and the laboratory is no exception. By embracing automation, labs can achieve greater efficiency, accuracy, and productivity while reducing errors and improving quality. In this comprehensive guide, we will explore laboratory automation in-depth, and look at the

Linkedin Facebook X-twitter Instagram Enabled by low volume non-contact dispensing A group from the Karolinska Institute in Stockholm (SE) performed a genomic sequencing study of the coronavirus, was conducted using a method called CUTseq (Zhang X. et al. 2019), which is a versatile technique for preparing multiplex DNA sequencing libraries from low-input samples. The research

Linkedin Facebook X-twitter Instagram Enabled by single prokaryotic cell sequencing using the B.SIGHT™ single bacteria dispenser A recent study from the Karlsruhe Institute of Technology and IMTEK department at the University of Freiburg in Germany, conducted using our single-bacteria dispenser, the B.SIGHT™, led to the identification of microbial “dark matter,” or uncultured microorganisms, in a

Linkedin Facebook X-twitter Instagram NEW PROTOCOL FOR FASTER AND MORE RELIABLE RNA COUNTING Postdoctoral researcher Christoph Ziegenhain has developed a new protocol for faster and more reliable RNA counting. Based at the Sandberg Lab at the Karolinska Institute in Stockholm, Sweden, Ziegenhain focuses primarily on single-cell quantitative transcriptomics methods. His latest paper, published in Nature

Linkedin Facebook X-twitter Instagram GENETICALLY ENGINEERED SINGLE-CELL CLONES Characterizing CRISPR/Cas9-engineered cells is a major priority for pharmaceutical companies, as well as for novel cellular therapeutic applications and regenerative medical uses. For this reason, the team at the Department of Microsystems Engineering at the University of Freiburg, under Dr. Stefan Zimmermann’s leadership, developed a new workflow

Linkedin Facebook X-twitter Instagram THE B.SIGHT ACCELERATES CULTIVATION OF HUMAN GUT BACTERIA USING SINGLE CELL DISPENSING TECHNOLOGY Prof. Thomas Clavel leads the Functional Microbiome research group at the Institute of Medical Microbiology, RWTH University Hospital, Aachen. The Clavel lab is dedicated to Functional Microbiome Research where they study gut microbial diversity by means of molecular